PIs must complete an IBC Annual Renewal each year to continue work for up to three years after the initial approval. After three years, the application must be resubmitted and reviewed by the committee.

What needs IBC approval?

• Recombinant or synthetic nucleic acid molecules
• Hazardous biological agents (virus, bacteria, fungi, parasite, prion, rickettsia etc.)
• Other potentially infectious materials (human or non-human primate blood, serum, plasma, body fluids, unfixed tissue, organ and cells)
• Biological toxins including select agent toxins
• Inactivated Biological Samples derived from BSL-3 or BSL-4 agents
• Attenuated pathogens derived from BSL-3 or BSL-4 agents
• Human gene transfer
• Transgenic animals or plants

Forms

• IBC Application (Doc)
• IBC Application A1- Recombinant DNA (rDNA) Registration Form (Doc)
• IBC Application A2 - Registration of BioSafety Level 2 (BSL-2) and Biosafety Level 3 (BSL-3) (Doc)
       Infections Agents, Select Agents, and Biological Toxins
• IBC Application A3 - BSL-3 Containment Measures (Doc)
• IBC Application A4 - Registration of Blood Borne Pathogens and Other Potentially Infectious Material (OPIM) (Doc)
• Hepatitis B Acceptance/Declination Form (Doc)

See NIH Guidelines (PDF) for additional information.